- 专利标题: ANTI-CD137 ANTIBODIES FOR COMBINATION WITH ANTI-PD-L1 ANTIBODIES
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申请号: US17040380申请日: 2019-03-15
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公开(公告)号: US20210054088A1公开(公告)日: 2021-02-25
- 发明人: Carmine CARPENITO , Yiwen LI
- 申请人: Eli Lilly and Company
- 申请人地址: US IN Indianapolis
- 专利权人: Eli Lilly and Company
- 当前专利权人: Eli Lilly and Company
- 当前专利权人地址: US IN Indianapolis
- 国际申请: PCT/US19/22391 WO 20190315
- 主分类号: C07K16/28
- IPC分类号: C07K16/28 ; A61K39/395 ; A61K45/06 ; A61P35/00
摘要:
The present invention relates to antibodies that bind to human CD137 and display agonist activity, and may be useful for treating solid and hematological tumors alone and in combination with anti-human PD-L1 antibodies, chemotherapy, and ionizing radiation.
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