Invention Application
- Patent Title: METHOD AND SYSTEM FOR TREATING CANCER
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Application No.: US17025269Application Date: 2020-09-18
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Publication No.: US20210077462A1Publication Date: 2021-03-18
- Inventor: Tomer SHLOMI , Won Dong LEE
- Applicant: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED
- Applicant Address: IL Haifa
- Assignee: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED
- Current Assignee: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED
- Current Assignee Address: IL Haifa
- Main IPC: A61K31/4162
- IPC: A61K31/4162 ; G01N33/574 ; A61P35/00

Abstract:
The invention provides a method for treating cancer in which a level of reduced folate carrier (RFC) or folylpolyglutamate synthetase (FPGS) in cancer cells of the biopsy is determined. If the level of RFC or FPGS in the cancer cells is below a threshold value, the cancer is treated with an inhibitor of serine-hydroxymethyltransferase (SHMT)1. If the level of RFC or FPGS in the cancer cells is above the threshold value, the cancer is treated with an inhibitor of SHMT2
Public/Granted literature
- US11826353B2 Method and system for treating cancer Public/Granted day:2023-11-28
Information query
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