An optical tomography device includes a carrier base, at least one slide rail, at least one sliding assembly, and at least one optical channel member. The carrier base has a through hole. The slide rail is located on the carrier base and extends toward the through hole. The sliding assembly includes a sliding block, a guiding rod, and an elastic component. The sliding block is slidably connected to the slide rail and has a first restriction portion. The guiding rod is slidably connected to the sliding block and has a second restriction portion. The elastic component is configured to be deformed by the first restriction portion and the second restriction portion. The optical channel member is coupled with the guiding rod.