Systems and methods are disclosed for data driven radio enhancement. For example, methods may include demodulating a radio signal to obtain a demodulated audio signal; determining a window of audio samples based on the demodulated audio signal; applying an audio enhancement network to the window of audio samples to obtain an enhanced audio segment, in which the audio enhancement network includes a machine learning network that has been trained using demodulated audio signals derived from radio signals; and storing, playing, or transmitting an enhanced audio signal based on the enhanced audio segment.