The present embodiments provide systems and methods for treating a medical condition. In one embodiment, the system comprises a stent having proximal and distal regions, and further having a delivery state and an expanded state. A therapeutic agent is disposed on a segment of the stent. The stent is disposed around an exterior surface of a core assembly in the delivery state. A coupling assembly releasably secures the proximal region of the stent to the exterior surface of the core assembly. The coupling assembly secures the stent to the core assembly for a predetermined period while the stent is in the expanded state and during release of the therapeutic agent at a target site. The coupling assembly further enables the stent to be disengaged from the core assembly and deployed in a bodily passageway.