- 专利标题: PEPTIDE AND USE THEREFOR
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申请号: US17044972申请日: 2019-04-25
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公开(公告)号: US20210163537A1公开(公告)日: 2021-06-03
- 发明人: Eisaku KONDO , Ken SAITO
- 申请人: NIIGATA UNIVERSITY
- 申请人地址: JP Niigata-shi, Niigata
- 专利权人: NIIGATA UNIVERSITY
- 当前专利权人: NIIGATA UNIVERSITY
- 当前专利权人地址: JP Niigata-shi, Niigata
- 优先权: JP2018088811 20180502
- 国际申请: PCT/JP2019/017629 WO 20190425
- 主分类号: C07K7/08
- IPC分类号: C07K7/08 ; C07K7/06 ; A61K47/64 ; A61P35/00 ; A61K49/00
摘要:
This peptide is composed of an amino acid sequence represented by general formula (I), and has a high degree of accumulation in cancer cells or cancer tissue in a digestive system. (In general formula (I), X11 is a peptide residue composed of an amino acid sequence of (a) or (b) below: (a) an amino acid sequence represented by any of SEQ ID NOs: 1 to 3, (b) an amino acid sequence including a sequence in which one or two amino acids have been deleted, substituted or added in an amino acid sequence represented by any of SEQ m NOs: 1 to 3; Y11 is a peptide linker composed of an amino acid residue of at least 1 but not more than 10 amino acids, wherein each amino acid residue is independently a glycine residue, a proline residue, a serine residue a cysteine residue or a lysine residue; X12 is either a peptide residue composed of an amino acid sequence of (a) or (b) above, or a retro-inverso peptide residue thereof; and n11 represents an integer of at least 1 but not more than 9.) [Formula 1] X11—(Y11—X12)n11 (I)
公开/授权文献
- US11447525B2 Peptide and use therefor 公开/授权日:2022-09-20
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