- 专利标题： USE OF OXYGENATED CHOLESTEROL SULFATES (OCS) TO TREAT INFLAMMATORY SKIN DISEASE AND SKIN LESIONS
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申请号： US17072994申请日： 2020-10-16
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公开(公告)号： US20210169902A1公开(公告)日： 2021-06-10
- 发明人: Shunlin Ren , WeiQi Lin , James E. Brown , Felix Theeuwes , Mee Jean Kim , Andrew R. Miksztal , Hongwei Wu , Min L. Lee , Huey-Ching Su , Wilma Tamraz
- 申请人： Virginia Commonwealth University , Durect Corporation
- 申请人地址： US VA Richmond; US CA Cupertino
- 专利权人： Virginia Commonwealth University,Durect Corporation
- 当前专利权人： Virginia Commonwealth University,Durect Corporation
- 当前专利权人地址： US VA Richmond; US CA Cupertino
- 主分类号： A61K31/575
- IPC分类号： A61K31/575 ; A61P17/06 ; A61K9/06 ; A61K47/10 ; A61K47/12 ; A61K47/14
摘要：
Methods of treating and prophylactically treating inflammatory skin diseases and skin lesions are provided. For instance, the methods may involve contacting the skin with an oxygenated cholesterol sulfate (OCS), e.g. 5-cholesten-3, 25-diol, 3-sulfate (25HC3S) or a pharmaceutically acceptable salt thereof.
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