Invention Application
- Patent Title: DC-SIGN ANTIBODY CONJUGATES COMPRISING STING AGONISTS
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Application No.: US16669291Application Date: 2019-10-30
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Publication No.: US20210170043A1Publication Date: 2021-06-10
- Inventor: Lisa BARNETT , Steven BENDER , Charles Y. CHO , Sarah COX , Jonathan Deane , Scott Martin GLASER , Xueshi Hao , Shailaja KASIBHATLA , Weijia OU , Tetsuo UNO , Yongqin WAN , Ben WEN , Tom Yao-Hsiang WU
- Applicant: NOVARTIS AG , ADURO BIOTECH, INC.
- Applicant Address: CH Basel; US CA Berkley
- Assignee: NOVARTIS AG,ADURO BIOTECH, INC.
- Current Assignee: NOVARTIS AG,ADURO BIOTECH, INC.
- Current Assignee Address: CH Basel; US CA Berkley
- Main IPC: A61K47/68
- IPC: A61K47/68 ; C07K16/28 ; A61K31/688 ; A61P35/00
Abstract:
Provided herein are immunoconjugates comprising an anti-DC-SIGN antibody conjugated to a STING agonist. Also disclosed are methods of making the immunoconjugates and methods of treating cancer using the immunoconjugates.
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