Invention Application
- Patent Title: FORMATION OF FUNCTIONALIZED NANOPARTICLES BY SUPRAMOLECULAR CO-ASSEMBLY
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Application No.: US16071168Application Date: 2017-01-19
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Publication No.: US20210170048A1Publication Date: 2021-06-10
- Inventor: Talia SHEKHTER ZEHAVI , Ehud GAZIT , Mor HERMAN-ORON , Genady KOSTENICH , Arie ORENSTEIN
- Applicant: RAMOT AT TEL-AVIV UNIVERSITY LTD. , TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD.
- Applicant Address: IL Tel Aviv; IL Ramat Gan
- Assignee: RAMOT AT TEL-AVIV UNIVERSITY LTD.,TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD.
- Current Assignee: RAMOT AT TEL-AVIV UNIVERSITY LTD.,TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD.
- Current Assignee Address: IL Tel Aviv; IL Ramat Gan
- International Application: PCT/IL2017/050080 WO 20170119
- Main IPC: A61K47/69
- IPC: A61K47/69 ; A61K47/60 ; A61K38/31 ; A61K47/64 ; A61P35/00
Abstract:
The present invention provides nanoparticle conjugates incorporating the self-assembling module diphenylalanine (FF) dipeptide into a bioactive moiety. The conjugate self-assembles to form distinct nanometric structures such as nanospheres. The present invention further provides nanoparticles formed by supramolecular co-assembly of the conjugates with a diphenylalanine (FF) dipeptide or analog thereof, to generate bioactive self-assembled nanostructures.
Information query
