A method for driving a display panel, a display drive circuit, a display device and a computer device are disclosed. After receiving an image to be displayed sent by a graphics processor, a data drive chip controls respective rows of sub-pixels containing a high-definition display area in a connected display panel to be scanned line by line according to a position of the high-definition display area in the image to be displayed, and at the same time, the data drive chip controls respective rows of sub-pixels containing only a low-definition display area in the display panel to be scanned per N rows simultaneously according to a position of the low-definition display area in the image to be displayed, where N is an even number greater than 1.