A method and system for the early detection of neurodegeneration are described. The method comprises the steps of: a) extracting samples of a plurality of eye-markers of a user from a video stream captured by a visible light camera; b) loading said samples of said plurality of eye-markers to a big data repository, analyzing and consolidating them into one biomarker for detecting multiple disorders by means of training a machine learning model; and c) determining the risk of said user to develop a neurodegenerative disease using said trained machine learning model as part of an early detection screening or diagnosis process.