- 专利标题: METHODS FOR DIAGNOSING FERTILITY OF EJACULATES FOR ARTIFICIAL INSEMINATION
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申请号: US17059946申请日: 2019-05-30
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公开(公告)号: US20210208154A1公开(公告)日: 2021-07-08
- 发明人: BARB A. COHEN
- 申请人: AREX LIFE SCIENCES, LLC
- 申请人地址: US MA WATERTOWN
- 专利权人: AREX LIFE SCIENCES, LLC
- 当前专利权人: AREX LIFE SCIENCES, LLC
- 当前专利权人地址: US MA WATERTOWN
- 国际申请: PCT/US2019/034601 WO 20190530
- 主分类号: G01N33/68
- IPC分类号: G01N33/68 ; C12N5/076 ; A01N1/02 ; A61B17/43 ; A61D19/02
摘要:
In accord with the present invention, the fertility quality of an ejaculate can be determined by assaying sperm, in aliquots of the ejaculate or of an ejaculate produced previously by the same male, at intervals over a period of time. Fertility quality is determined by the number of times the level of expression of a marker on the sperm goes through a maximum level of expression during the period of time and if desired by sperm state and fertilization procedure used. The marker should be capable of correlation with the level of Fc receptor (FcR) expression on the sperm. The fertility quality of the ejaculate is related to the number of times a maximum level of expression is reached.
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