A touch panel and a manufacturing method thereof, and a touch display device are provided. The touch panel includes a touch region, the touch region includes: a plurality of conductive portions arranged at intervals, a region in which the plurality of conductive portions are located including an electrode region; a plurality of electrical connection portions electrically connecting the conductive portions located in the electrode region to form a plurality of first electrodes extending in a first direction and a plurality of second electrodes extending in a second direction, the plurality of first electrodes being insulated from the plurality of second electrodes. In the second direction, each of the plurality of first electrodes includes at least two of the plurality of conductive portions; in the first direction, each of the plurality of second electrodes includes at least two of the plurality of conductive portions.