The invention relates to a centrifuge (10), having a drive shaft (12), a rotor (14), which is mounted on the drive shaft (12) and is axially removable in a removal direction (26), a quick closure (20), which operates between the rotor (14) and the drive shaft (12) and by means of which the rotor (14) can be fixed relative to the drive shaft (12) in the removal direction (26), a thrust bearing (44) connected to the drive shaft (12), a locking bearing (24) connected to the rotor (14), at least one blocking element (38), which, when activated, fixes the rotor (14) relative to the drive shaft (12) and operates between the locking bearing (24) of the rotor (14) and the thrust bearing (44) of the drive shaft (12). The pivot axis (38b) is aligned perpendicular to a straight line parallel to the drive shaft (12) and the blocking element (38) has a cardan shaft (38a), which is rotatable about the pivot axis (38b), and is connected to a bearing (40) via the cardan shaft (38a).