A display substrate, a display module and a method for driving the display module, and a display apparatus are provided. The display substrate includes a plurality of pixel units. At least one pixel unit includes: a first sub-pixel; a color-changing layer covering a part of a light-emitting surface of the first sub-pixel, the color-changing layer being able to be switched between a first state and a second state, and the color-changing layer being configured to enable a first wavelength light emitted by the first sub-pixel to pass through the color-changing layer in the first state; and a light-emitting layer located on a side of the color-changing layer that is away from the first sub-pixel, and configured to emit a second wavelength light under excitation of the first wavelength light. The second wavelength light is an invisible light.