- 专利标题： SUBSTITUTED INDOLE COMPOUNDS
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申请号： US16763670申请日： 2018-11-13
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公开(公告)号： US20210253593A1公开(公告)日： 2021-08-19
- 发明人: Alaric J. Dyckman , Dharmpal S. Dodd , Christopher P. Mussari , Trevor C. Sherwood , John L. Gilmore , Tasir Shamsul Haque , Brian K. Whiteley , David R. Tortolani , Shoshana L. Posy , John E. Macor , Louis J. Lombardo , Ramesh Kumar Sistla , Anupama Kandhi Ramachandra Reddy , Subramanya Hegde , Laxman Pasunoori , Sreekantha Ratna Kumar
- 申请人： BRISTOL-MYERS SQUIBB COMPANY
- 申请人地址： US NJ Princeton
- 专利权人： BRISTOL-MYERS SQUIBB COMPANY
- 当前专利权人： BRISTOL-MYERS SQUIBB COMPANY
- 当前专利权人地址： US NJ Princeton
- 国际申请： PCT/US2018/060590 WO 20181113
- 主分类号： C07D498/04
- IPC分类号： C07D498/04 ; C07D413/14 ; C07D471/04 ; C07D487/04 ; C07D417/14 ; C07D405/14 ; C07D513/04 ; C07D401/14 ; C07D495/04
摘要：
Disclosed are compounds of Formula (I) or salts thereof, wherein Ring Het, R1, R2, R3, R4, R5, m, n, and p are defined herein. Also disclosed are methods of using such compounds as inhibitors of signaling through Toll-like receptor 7, or 8, or 9, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating inflammatory and autoimmune diseases.
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