- 专利标题: PYRIMIDINONES AS PI3K INHIBITORS
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申请号: US17038165申请日: 2020-09-30
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公开(公告)号: US20210253601A1公开(公告)日: 2021-08-19
- 发明人: Yun-Long Li , Brian W. Metcalf , Andrew P. Combs
- 申请人: Incyte Corporation , Incyte Holdings Corporation
- 申请人地址: US DE Wilmington; US DE Wilmington
- 专利权人: Incyte Corporation,Incyte Holdings Corporation
- 当前专利权人: Incyte Corporation,Incyte Holdings Corporation
- 当前专利权人地址: US DE Wilmington; US DE Wilmington
- 主分类号: C07D519/00
- IPC分类号: C07D519/00 ; C07D471/04 ; C07D513/04 ; C07D487/04
摘要:
The present invention provides pyrimidinones that modulate the activity of phosphoinositide 3-kinases (PI3Ks) and are useful in the treatment of diseases related to the activity of PI3Ks including, for example, inflammatory disorders, immune-based disorders, cancer, and other diseases.
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