Circuit and method for preventing screen flickering, a drive circuit for a display panel, and a display apparatus are provided, relating to the field of display technology. The circuit for preventing screen flickering includes a control sub-circuit configured to control a gate drive circuit of the display panel to output a gate cut-off level during a power-on period of the display panel. The gate drive circuit of the display panel is controlled to output the gate cut-off level during the power-on period, the gate cut-off level is provided to gate lines of the display panel such that TFTs connected to the gate lines are in cut-off state during the power-on period.