- 专利标题： MICRORNA-134 BIOMARKER
-
申请号： US17183273申请日： 2021-02-23
-
公开(公告)号： US20210270845A1公开(公告)日： 2021-09-02
- 发明人: Jesper Worm , Lukasz Kielpinski
- 申请人： Roche Innovation Center Copenhagen A/S
- 申请人地址： DK Horsholm
- 专利权人： Roche Innovation Center Copenhagen A/S
- 当前专利权人： Roche Innovation Center Copenhagen A/S
- 当前专利权人地址： DK Horsholm
- 优先权： EP18190523.3 20180823
- 主分类号： G01N33/68
- IPC分类号： G01N33/68 ; C12N15/113
摘要：
The invention relates to the field of secondary markers for microRNA activity, and in particular the invention relates to the identification of Serpine1 as a mRNA which is repressed by microRNA-134 in neuronal cells, and the use of Serpine1 mRNA or protein as a biomarker for microRNA-134 modulation, such as a biomarker for antisense oligonucleotide inhibitors of microRNA-134.
信息查询
IPC分类:
