- 专利标题： REGULATING IL-4 AND IL-13 LEVELS BY BLOCKING HIGH AFFINITY BINDING BY IL-3, IL-5 AND GM-CSF TO THEIR COMMON RECEPTOR
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申请号： US17150789申请日： 2021-01-15
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公开(公告)号： US20210317218A1公开(公告)日： 2021-10-14
- 发明人: Angel LOPEZ , Paul FOSTER
- 申请人： CENTRAL ADELAIDE LOCAL HEALTH NETWORK INC. , NEWCASTLE INNOVATION LTD.
- 申请人地址： AU Adelaide; AU Calanghan
- 专利权人： CENTRAL ADELAIDE LOCAL HEALTH NETWORK INC.,NEWCASTLE INNOVATION LTD.
- 当前专利权人： CENTRAL ADELAIDE LOCAL HEALTH NETWORK INC.,NEWCASTLE INNOVATION LTD.
- 当前专利权人地址： AU Adelaide; AU Calanghan
- 优先权： AU2007903749 20070711
- 主分类号： C07K16/28
- IPC分类号： C07K16/28 ; A61K45/06 ; A61K31/00 ; A61K31/57 ; A61K39/395
摘要：
A method of reducing IL-4 and/or IL-13 levels in the lung of a mammal with elevated levels thereof, includes the step of administering to the mammal an effective amount of a βc receptor blocker capable of blocking the binding of all three of IL-3, IL-5 and GM-CSF to the βc common chain to thereby reduce the IL-4 and/or IL-13 levels.
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