Invention Application
- Patent Title: NEUROACTIVE STEROIDS SUBSTITUTED IN POSITION 10 WITH A CYCLIC GROUP FOR USE IN THE TREATMENT OF CNS DISORDERS
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Application No.: US17284206Application Date: 2019-10-11
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Publication No.: US20210340172A1Publication Date: 2021-11-04
- Inventor: Maria Jesus BLANCO-PILLADO , Francesco G. SALITURO , Marshall Lee MORNINGSTAR
- Applicant: SAGE THERAPEUTICS, INC.
- Applicant Address: US MA Cambridge
- Assignee: SAGE THERAPEUTICS, INC.
- Current Assignee: SAGE THERAPEUTICS, INC.
- Current Assignee Address: US MA Cambridge
- International Application: PCT/US2019/055926 WO 20191011
- Main IPC: C07J43/00
- IPC: C07J43/00 ; C07J7/00
Abstract:
Provided herein is a compound of Formula (I) or a pharmaceutically acceptable salt thereof, wherein n, R19, R5, R3a, R6a, R6b, R1, R2a, R2b, R4a, R4b, R7a, R7b, R11a, R11b, R12a, R12b, R17b, R15a, R15b, R16a and R16b are defined herein. Also provided herein are pharmaceutical compositions comprising a compound of Formula (I) and methods of using the compounds, e.g., in the treatment of CNS-related disorders.
Public/Granted literature
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