Universal control circuitry for an electro-hydraulic valve actuator system includes logic gate circuitry to control one or more of a closing solenoid valve, an opening solenoid valve, an emergency shutdown solenoid valve, and a hydraulic fluid pump motor to route hydraulic fluid through a hydraulic circuit to actuate a valve via a hydraulic actuator according to received commands. The universal control circuitry is configured to control operation for multiple different configurations of a hydraulic valve actuator system including double-acting configurations, single-acting spring-to-open configurations, and single-acting spring-to-close configurations, each with or without an emergency shutdown arrangement (which may be configured to trip based on an external shutdown input alone or in combination with a local system power failure), a hydraulic accumulator, and maintained or momentary input commands.