- 专利标题： ANTI-IgE ANTIBODY SPECIFICALLY BINDING TO MEMBRANE-BOUND IgE ANTIBODY OF IgE ANTIBODY-PRODUCING B CELLS AND METHOD FOR DIAGNOSING AND TREATING ALLERGIC SYMPTOMS USING THE SAME
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申请号： US17278164申请日： 2019-09-20
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公开(公告)号： US20210355237A1公开(公告)日： 2021-11-18
- 发明人: Kenichi MASUDA , Takashi SAITO
- 申请人： RIKEN , ANIMAL ALLERGY CLINICAL LABORATORIES INC.
- 申请人地址： JP Saitama; JP Kanagawa
- 专利权人： RIKEN,ANIMAL ALLERGY CLINICAL LABORATORIES INC.
- 当前专利权人： RIKEN,ANIMAL ALLERGY CLINICAL LABORATORIES INC.
- 当前专利权人地址： JP Saitama; JP Kanagawa
- 优先权： JP2018-176768 20180921
- 国际申请： PCT/JP2019/036864 WO 20190920
- 主分类号： C07K16/42
- IPC分类号： C07K16/42 ; G01N33/68
摘要：
The present invention provides an antibody specific to IgE antibody-producing B cells or an antibody binding fragment thereof. More specifically, the present invention provides an isolated monoclonal antibody or an antigen binding fragment thereof that binds to a peptide having a sequence consisting of an amino acid sequence set forth in SEQ ID NO: 1 or 18, and (1) binds to IgE antibody on a B cell surface and/or (2) binds to IgE antibody heated at 56° C.
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