Disclosed is an assembling and centering structure for a processing tool, the structure having a clamping handle (10), a processing head (20), and a fastening member (30) for connecting and fixing the clamping handle (10) and the processing head (20). An end face accommodation groove (100) of the clamping handle (10) is formed with a concave part (11) and a centering hole (12). The processing head (20) is formed with a convex part (211) and a centering post (222), the convex part (211) matches the concave part (11), and the centering post (222) matches the centering hole (12). Thus, it can be ensured that after assembly, the central axis of rotation of the clamping handle (10) is in a straight line with the central axis of rotation of the processing head (20).