The present disclosure relates to an air cleaner with an improved locking structure. The air cleaner includes a cabinet, a panel having a plurality of holes for discharging air to the front of the cabinet and detachably mounted on the cabinet, and a locking device to detachably connect the cabinet and the panel, wherein the locking device includes a first locking member disposed on the panel, and a second locking member disposed in the cabinet to lock or unlock the first locking member by being rotated by pressing of the first locking member.