Disclosed are a pixel circuit comprising an optical fingerprint sensing circuit, a method of driving a pixel circuit comprising an optical fingerprint sensing circuit, and a display device comprising a pixel circuit comprising an optical fingerprint sensing circuit. According to the present disclosure, the pixel circuit comprising an optical fingerprint sensing circuit comprises a pixel control circuit, the pixel control circuit comprising: a first photodetector which receives a light and generates a first signal; a second photodetector which receives a light and generates a second signal; and a self-illuminator which receives differential signals of the first signal and second signal and outputs an output signal, includes at least one transistor component and at least one capacitor component, and outputs a light on the basis of a data signal.