- 专利标题: GENERATION OF ANTIBODY-DERIVED POLYPEPTIDES BY POLYPEPTIDE CHAIN EXCHANGE
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申请号: US17506993申请日: 2021-10-21
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公开(公告)号: US20220033525A1公开(公告)日: 2022-02-03
- 发明人: Ulrich Brinkmann , Can Martin Buldun , Stefan Dengle , Steffen Dickopf , Guy Georges , Eike Hoffmann , Sabine Imhof-Jung , David Zilian
- 申请人: Hoffmann-La Roche Inc.
- 申请人地址: US NJ Little Falls
- 专利权人: Hoffmann-La Roche Inc.
- 当前专利权人: Hoffmann-La Roche Inc.
- 当前专利权人地址: US NJ Little Falls
- 优先权: EP19171068.0 20190425
- 主分类号: C07K16/44
- IPC分类号: C07K16/44 ; C07K16/28 ; G01N33/68
摘要:
The present invention relates to a set of heterodimeric polypeptides and its uses, e.g. for generating multispecific antigen binders by polypeptide chain exchange.
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