A system for determining real time cluster efficiency for a pumping operation in a wellbore includes a pump, a surface sensor, a downhole sensor system, and a computing device. The pump can pump slurry or diverter material in the wellbore. The surface sensor can be positioned at a surface of the wellbore to detect surface data about the pump. The downhole sensor system can be positioned in the wellbore to detect downhole data about an environment of the wellbore. The computing device can receive the surface data from the surface sensor, receive the downhole data from the downhole sensor system, apply the surface data and the downhole data to a long short-term memory (LSTM) neural network to produce a predicted cluster efficiency associated with operational settings of the pump, and control the pump using the operational settings to achieve the predicted cluster efficiency.