- 专利标题: ANAEROBIC FERMENTATIVE PRODUCTION OF FURANDIMETHANOL AND ENZYMATIC PRODUCTION OF FURANDICARBOXYLIC ACID
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申请号: US17463988申请日: 2021-09-01
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公开(公告)号: US20220064682A1公开(公告)日: 2022-03-03
- 发明人: Iuri Estrada GOUVEA , Ana Karina BRAMBILLA COSTA , Marcos Rogerio SIMOES , Veronica Leite QUEIROZ , Aline Silva ROMÃO DUMARESQ
- 申请人: Braskem S.A.
- 申请人地址: BR Camacari
- 专利权人: Braskem S.A.
- 当前专利权人: Braskem S.A.
- 当前专利权人地址: BR Camacari
- 主分类号: C12P17/04
- IPC分类号: C12P17/04 ; C12N1/16 ; C12N15/81
摘要:
The present disclosure provides recombinant microorganisms and methods for the anaerobic production of 2,4-furandimethanol from one or more carbon sources. The microorganisms and methods provide redox-balanced and ATP positive pathways for co-producing 2,4-furandimethanol with ethanol and for co-producing 2,4-furandimethanol with ethanol and acetone and/or isopropanol. The method provides recombinant microorganisms that express endogenous and/or exogenous nucleic acid molecules encoding polypeptides that catalyze the conversion of a carbon source into 2,4-furandimethanol and that couple the 2,4-furandimethanol pathway with an additional metabolic pathway. The present disclosure further provides enzymatic production of 2,4-furandicarboxylic acid.
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