- 专利标题: Combination therapy of PD-1-targeted IL-2 variant immunocytokines and antibodies against human PD-L1
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申请号: US17464518申请日: 2021-09-01
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公开(公告)号: US20220072103A1公开(公告)日: 2022-03-10
- 发明人: Laura CODARRI DEAK , Douglas Hanahan , Christian Klein , Valeria Nicolini , Pablo Umana , Stephen Wullschleger
- 申请人: Hoffmann-La Roche Inc.
- 申请人地址: US NJ Little Falls
- 专利权人: Hoffmann-La Roche Inc.
- 当前专利权人: Hoffmann-La Roche Inc.
- 当前专利权人地址: US NJ Little Falls
- 主分类号: A61K38/20
- IPC分类号: A61K38/20 ; A61K39/395 ; A61K35/17 ; A61K35/15 ; A61K38/17 ; A61P35/00
摘要:
The present invention relates to the combination therapy of specific PD-1-targeted IL-2 variant immunocytokines with specific antibodies which bind human PD-L1.
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