Examples of the present disclosure relate to a distributed CDN comprised of CDN nodes that each have a compute engine and a data store. Compute engines may be used to execute software associated with computing functionality of the distributed CDN and may be reconfigured according to changing conditions to adapt computing functionality to current or expected demand. Nodes may communicate with one another via an overlay network. A node may determine whether it should process a request or generate a route via the overlay network to the remote node, thereby enabling the remote node to process the request. In another example, a node may receive a request for a compute resource that is not currently provided by the node. The compute engine of the node may be reconfigured to provide the compute resource, thereby enabling the node to service the request rather than redirect the request to a different node.