Invention Application
- Patent Title: THERAPEUTIC COMBINATIONS AND COMPOSITIONS FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASE
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Application No.: US17427811Application Date: 2020-02-04
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Publication No.: US20220125795A1Publication Date: 2022-04-28
- Inventor: Gerard DIJKSTRA , Klaas Nico FABER , Hermanus Jozef Martinus HARMSEN , Robert STEINERT , Wilbert SYBESMA , Araksya TOPCHYAN
- Applicant: RIJKSUNIVERSITEIT GRONINGEN , DSM IP ASSETS B.V. , ACADEMISCH ZIEKENHUIS GRONINGEN
- Applicant Address: NL Groningen; NL Heerlen; NL Groningen
- Assignee: RIJKSUNIVERSITEIT GRONINGEN,DSM IP ASSETS B.V.,ACADEMISCH ZIEKENHUIS GRONINGEN
- Current Assignee: RIJKSUNIVERSITEIT GRONINGEN,DSM IP ASSETS B.V.,ACADEMISCH ZIEKENHUIS GRONINGEN
- Current Assignee Address: NL Groningen; NL Heerlen; NL Groningen
- Priority: EP19155289.2 20190204,EP19155314.8 20190204
- International Application: PCT/EP2020/052649 WO 20200204
- Main IPC: A61K31/52
- IPC: A61K31/52 ; A61P1/00 ; A61K31/525
Abstract:
The present invention relates to pharmaceutical combinations of at least one thiopurine and/or at least a pharmaceutically acceptable salt and/or at least one prodrug thereof and riboflavin to treat patients suffering from inflammatory bowel disease (IBD) or other inflammatory conditions. This invention also relates to additive and/or combinations of at least one thiopurine and riboflavin. This invention is also related to a method for the treatment or prophylaxis of IBD or other inflammatory conditions, which method comprises administering a therapeutically effective amount of thiopurine and riboflavin.
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