Invention Application
- Patent Title: THERAPEUTIC COMPOUNDS AND USES THEREOF
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Application No.: US17570139Application Date: 2022-01-06
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Publication No.: US20220127265A1Publication Date: 2022-04-28
- Inventor: Patrick Cyr , Sarah Bronner , F. Anthony Romero , Steven Magnuson , Vickie Hsiao-Wei Tsui , Jeremy M. Murray , John Wai , Kwong Wah Lai , Fei Wang , Kevin X. Chen
- Applicant: GENENTECH, INC. , CONSTELLATION PHARMACEUTICALS, INC.
- Applicant Address: US CA South San Francisco; US MA Cambridge
- Assignee: GENENTECH, INC.,CONSTELLATION PHARMACEUTICALS, INC.
- Current Assignee: GENENTECH, INC.,CONSTELLATION PHARMACEUTICALS, INC.
- Current Assignee Address: US CA South San Francisco; US MA Cambridge
- Priority: CNPCT/CN2016/083118 20160524
- Main IPC: C07D471/04
- IPC: C07D471/04 ; C07D519/00
Abstract:
The present invention relates to a compound formula (I): and to salts thereof, wherein R1, R2 X, and Y have any of the values defined herein, and compositions and uses thereof. The compounds are useful as inhibitors of CBP and/or EP300. Also included are pharmaceutical compositions comprising a compound of formula (I) or a pharmaceutically acceptable salt thereof, and methods of using such compounds and salts in the treatment of various CBP and/or EP300-mediated disorders.
Information query
