Invention Application
- Patent Title: TOPICAL COMPOSITION
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Application No.: US17498147Application Date: 2021-10-11
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Publication No.: US20220133677A1Publication Date: 2022-05-05
- Inventor: Yoshiaki KAWAGUCHI , Tammam ALAMA
- Applicant: The Mentholatum Company , ROHTO Pharmaceutical Co., Ltd.
- Applicant Address: US NY Orchard Park; JP Osaka
- Assignee: The Mentholatum Company,ROHTO Pharmaceutical Co., Ltd.
- Current Assignee: The Mentholatum Company,ROHTO Pharmaceutical Co., Ltd.
- Current Assignee Address: US NY Orchard Park; JP Osaka
- Main IPC: A61K31/325
- IPC: A61K31/325 ; A61K9/00 ; A61K9/06

Abstract:
Problem: To provide a topical composition having excellent permeability in the stratum corneum. Solution: A topical composition is prepared that comprises: (A) one antifungal agent or two or more antifungal agents selected from the group consisting of tolnaftate and pharmaceutically acceptable salts thereof; and (B) at least one compound selected from the group consisting of ester compounds of fatty acids having from 8 to 18 carbon atoms and dihydric alcohols having from 2 to 4 carbon atoms, lysine acyl glutamate, lysine diacyl glutamate, pharmaceutically acceptable salts of lysine acyl glutamate or lysine diacyl glutamate, diethylene glycol-based glycol ethers, cyclohexanedicarboxylic acid polyoxyethylene alkyl ethers, mannosylerythritol lipids, and sucrose fatty acid esters.
Public/Granted literature
- US12090133B2 Topical composition Public/Granted day:2024-09-17
Information query