Invention Application
- Patent Title: FLOW-THROUGH PARAMAGNETIC PARTICLE-BASED CELL SEPARATION AND PARAMAGNETIC PARTICLE REMOVAL
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Application No.: US17503186Application Date: 2021-10-15
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Publication No.: US20220135931A1Publication Date: 2022-05-05
- Inventor: Fabio FACHIN , Rodney RIETZE , Michael R. GREENE , Lan CAO
- Applicant: Novartis AG , The Trustees of the University of Pennsylvania
- Applicant Address: CH Basel; US PA Philadelphia
- Assignee: Novartis AG,The Trustees of the University of Pennsylvania
- Current Assignee: Novartis AG,The Trustees of the University of Pennsylvania
- Current Assignee Address: CH Basel; US PA Philadelphia
- Main IPC: C12M1/00
- IPC: C12M1/00 ; B03C1/30 ; B03C1/033 ; B03C1/28 ; B03C1/01 ; C07K16/28 ; C12M1/12 ; C12N13/00
Abstract:
The present disclosure relates to systems and methods for flow-through separation of paramagnetic particle-bound cells in a cell suspension containing both bound and unbound cells as well as systems and methods for removing paramagnetic particles from paramagnetic particle-bound cells or from a cell suspension with unbound cells. It further relates to a flow-through magnetic separation/debeading module and a flow-through spinning membrane debeading module.
Public/Granted literature
- US11912978B2 Flow-through paramagnetic particle-based cell separation and paramagnetic particle removal Public/Granted day:2024-02-27
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