A touch panel and a touch panel operation method are disposed. The touch panel includes an active region and a non-active region in an operating state, and the touch panel includes a plurality of sensing electrodes and a controller. The plurality of sensing electrodes are disposed in the active region and the non-active region. The controller receives an active touch signal from the plurality of sensing electrodes located in the active region and a non-active touch signal from the plurality of the sensing electrodes located in the non-active region. The controller manages the active touch signal and the non-active touch signal, so that only the active touch signal is subjected to a subsequent process.