A method for transmitting and receiving HARQ-ACK information in a wireless communication system and a device therefor are disclosed. Specifically, a method of transmitting, by a user equipment (UE), HARQ-ACK information in a wireless communication system comprises receiving first downlink control information (DCI) based on a first control resource set group and second DCI based on a second control resource set group; determining a physical uplink control channel (PUCCH) resource for a transmission of the HARQ-ACK information; and transmitting the HARQ-ACK information based on the determined PUCCH resource, wherein the first DCI and the second DCI are indexed based on (i) an index of a physical downlink control channel (PDCCH) related monitoring occasion, (ii) a cell index, and (iii) an index associated with each control resource set group, and wherein the PUCCH resource is determined based on a last DCI among the first DCI and the second DCI.