Invention Application
- Patent Title: ROTARY PLATFORM FOR CELL LYSING AND PURIFICATION AND METHOD OF USE
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Application No.: US17595802Application Date: 2020-05-08
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Publication No.: US20220143596A1Publication Date: 2022-05-12
- Inventor: Jason Bryant , Eric Yeaton , Dan Harris , Josiah Hackendorf , Steven Allen , Mark Talmer
- Applicant: Siemens Healthcare Diagnostics Inc.
- Applicant Address: US NY Tarrytown
- Assignee: Siemens Healthcare Diagnostics Inc.
- Current Assignee: Siemens Healthcare Diagnostics Inc.
- Current Assignee Address: US NY Tarrytown
- International Application: PCT/US2020/032108 WO 20200508
- Main IPC: B01L3/00
- IPC: B01L3/00 ; C12N1/06

Abstract:
Magnetic beads having cell components of interest are translated between a sequence of processing wells in a tray without need for pipetting. The circular tray contains one or more sequences of wells each interconnected by a respective channel. The tray is rotated about a central axis and a magnet, an agitator, and a heater provided external to the tray enable magnetic bead translation, mixing, and incubation, respectively. The magnet proximate a well forms a cluster of beads. Manipulation of the tray in rotation and elevation results in translation of the cluster from one well, through a channel, and into an adjacent well. The well containing a cluster may be rotationally positioned in front of the agitator, the agitator extended into contact with the well, followed by mechanical agitation. The heater, disposed beneath the tray, may accept a well lowered thereto for selective heating.
Public/Granted literature
- US11446652B2 Rotary platform for cell lysing and purification and method of use Public/Granted day:2022-09-20
Information query
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