Invention Application
- Patent Title: METHODS OF TREATING SYSTEMIC LUPUS ERYTHEMATOSUS USING A DOMAIN ANTIBODY DIRECTED AGAINST CD28
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Application No.: US17584207Application Date: 2022-01-25
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Publication No.: US20220144951A1Publication Date: 2022-05-12
- Inventor: Xavier Valencia , John P. Throup , Steven G. Nadler , Suzanne J. Suchard , Dominique Duchesne , Xiaoni Liu , Rong Shi , Diane E. Shevell , Jenny H. Xie , Marek Honczarenko
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee Address: US NJ Princeton
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K47/60 ; A61K39/395 ; A61K45/06
Abstract:
Methods of treating autoimmune diseases, such as systemic lupus erythematosus using domain antibodies that specifically bind human CD28 are provided. The methods may comprise at least one administration cycle comprising one dose of the domain antibody. The method reduces symptoms of systemic lupus erythematosus compared to placebo.
Public/Granted literature
- US11912769B2 Methods of treating systemic lupus erythematosus using a domain antibody directed against CD28 Public/Granted day:2024-02-27
Information query
