Provided are a human-machine interaction method, a system, a processing device and a computer readable storage medium, wherein the method includes: controlling a 3D display to output a 3D view to present a virtual target object; receiving a user image taken by a sight tracking camera, and detecting an eye gaze region according to the user image; receiving a hand image taken by a gesture detection camera, and detecting whether a user's hand collides with the virtual target object and/or grabs the virtual target object according to the hand image; controlling playing of the 3D view according to whether human eyes gaze at the virtual target object, the user's hand collides with the virtual target, and grasps the virtual target object.