发明申请
- 专利标题: COMPOSITIONS AND METHODS FOR INCREASING MUSCLE MASS AND OXIDATIVE METABOLISM
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申请号: US17602989申请日: 2020-04-09
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公开(公告)号: US20220162198A1公开(公告)日: 2022-05-26
- 发明人: Melissa SPENCER , Varghese JOHN , Irina KRAMEROVA , Jian LIU , Jesus CAMPAGNA , Barbara JAGODZINSKA
- 申请人: The Regents of the University of California
- 申请人地址: US CA Oakland
- 专利权人: The Regents of the University of California
- 当前专利权人: The Regents of the University of California
- 当前专利权人地址: US CA Oakland
- 国际申请: PCT/US2020/027510 WO 20200409
- 主分类号: C07D405/12
- IPC分类号: C07D405/12 ; C07D405/14 ; C07D491/056 ; A61P21/00
摘要:
Compositions and methods of use for a compound having a chemical structure of Formula (I) and/or Formula (VII), or a pharmaceutically acceptable salt or solvate thereof, to increase muscle mass, muscle oxidative capacity, and muscle function and to treat muscular dystrophy, in particular limb girdle muscular dystrophy type 2A/R1/D1 are disclosed.