The present disclosure provides a color filter substrate, including: a base substrate, and a light-shielding pattern on the base substrate and having a plurality of openings to define a plurality of pixel regions, wherein each of the plurality of pixel regions at least includes a color filtering region, and a color filtering layer is filled in each color filtering region, and at least one of the plurality of pixel regions further includes at least one transparent region, each of which is filled with a transparent non-filtering layer. The present disclosure further provides a reflective display panel and a manufacturing method for a color filter substrate.