An air cleaner assembly including a housing, a filter cartridge removably positioned within the inner opening of the housing, wherein the filter cartridge includes a media pack and a sealing member that includes a pinch seal portion spaced from an outer surface of the media pack and positionable within a housing channel of the housing when the filter cartridge is positioned within the inner opening of the housing, and a precleaner assembly positionable between the filter cartridge and the inlet end of the housing, wherein the precleaner includes a base member having a lower edge, and an access cover removably attachable to an inlet end of the housing, wherein the precleaner assembly is sealable within the air cleaner assembly by pressing the lower edge of the base member against a top surface of the sealing member.