A system for providing surgical planning and guidance with three-dimensional visualization is disclosed. In particular, the system obtains an image set of an anatomy of interest of a subject, and renders the image set on a user interface using volume rendering. Notably, the system accomplishes the foregoing without generating surface models or conducting bone contouring. The system may, during generation of an implant plan for implanting an implant onto the anatomy of interest, suggest landmark points in the volume rendered image set. Once the landmark points are confirmed, the system may facilitate implant positioning via implant controls. The system conducts a registration process to confirm a match between the physical anatomy of interest and the information contained in volume-rendered image set in the plan. If there is a match, the system may facilitate performance of a surgical procedure for implanting the implant onto the anatomy of interest of the subject.