An air treatment system includes a cyclone filter and an electrostatic filtration system. The cyclone filter may include a cyclone chamber, a cyclone chamber inlet configured to receive air including suspended particulates, and a cyclone chamber outlet configured to output treated air toward a respiratory interface, e.g., a mask or face shield. The cyclone filter produces a rotational airflow that removes at least some particulates from the air in the cyclone filter. The electrostatic filtration system is configured to charge the particulates in the cyclone chamber with a first polarity to produce an electrostatic attraction of the particulates to a particulate removal system charged with an opposite second polarity, to remove additional particulates from the cyclone filter. The air treatment system may also include an ultraviolet purification system to deliver ultraviolet radiation (e.g., UVC radiation) to kill, destroy or otherwise affect organic particulates in the air being treated.