Invention Application
- Patent Title: ANTIBODY HEAVY CHAIN CONSTANT DOMAINS
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Application No.: US17570954Application Date: 2022-01-07
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Publication No.: US20220185877A1Publication Date: 2022-06-16
- Inventor: Brenda L. Stevens , Mark W. Rixon , Scott R. Presnell
- Applicant: Bristol-Myers Squibb Company
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Main IPC: C07K16/24
- IPC: C07K16/24 ; C07K16/46

Abstract:
The present invention relates to antagonizing the activity of IL-17A, IL-17F and IL-23 using bispecific antibodies that comprise a binding entity that is cross-reactive for IL-17A and IL-17F and a binding entity that binds IL-23p19. The present invention relates to novel bispecific antibody formats and methods of using the same.
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