Invention Application
- Patent Title: METHODS OF TREATING BREAST CANCER WITH TETRAHYDRONAPHTHALENE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADER
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Application No.: US17548842Application Date: 2021-12-13
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Publication No.: US20220193072A1Publication Date: 2022-06-23
- Inventor: Xin CHEN , Andrew P. CREW , John FLANAGAN , Sheryl Maxine GOUGH , Royal J. HASKELL, III , Marcia Dougan MOORE , Yimin QIAN , Ian Charles Anthony TAYLOR , Jing WANG
- Applicant: Arvinas Operations, Inc.
- Applicant Address: US CT New Haven
- Assignee: Arvinas Operations, Inc.
- Current Assignee: Arvinas Operations, Inc.
- Current Assignee Address: US CT New Haven
- Main IPC: A61K31/497
- IPC: A61K31/497 ; A61P35/04 ; A61K31/519
Abstract:
The present application relates to treating and/or preventing breast cancer, including locally advanced or metastatic, ER+, HER2− breast cancer, in a subject in need of treatment, comprising administering a compound of Formula (I), or a pharmaceutically acceptable salt, enantiomer, stereoisomer, solvate, polymorph, isotopic derivative, or prodrug thereof, wherein R1, R2, R3, R4, m, and n are defined herein.
Information query
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