Invention Application
- Patent Title: IMMUNE CELL CONTAINING TUMOR ANTIGEN RECOGNITION RECEPTOR AND APPLICATION THEREOF
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Application No.: US17600904Application Date: 2020-04-03
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Publication No.: US20220195397A1Publication Date: 2022-06-23
- Inventor: Xuemei LIAO , Jingwei HUANG , Zhuo CHEN , Manman XIE , Andi LI , Yang LIU , Guangxin XIA , Yanjun LIU , Ying KE
- Applicant: SHANGHAI PHARMACEUTICALS HOLDING CO., LTD.
- Applicant Address: CN Shanghai
- Assignee: SHANGHAI PHARMACEUTICALS HOLDING CO., LTD.
- Current Assignee: SHANGHAI PHARMACEUTICALS HOLDING CO., LTD.
- Current Assignee Address: CN Shanghai
- Priority: CN201910271566.0 20190404
- International Application: PCT/CN2020/083129 WO 20200403
- Main IPC: C12N5/10
- IPC: C12N5/10 ; A61K39/00 ; A61P35/00 ; C07K16/30 ; C07K14/725

Abstract:
A modified immune effector cell and a use thereof, a cell population containing the immune effector cell, and a pharmaceutical composition. The expression and/or activity of an S1PR1 protein of the modified immune effector cell is up-regulated.
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