Invention Application
- Patent Title: SERUM ALBUMIN-BINDING FIBRONECTIN TYPE III DOMAINS
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Application No.: US17527238Application Date: 2021-11-16
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Publication No.: US20220204589A1Publication Date: 2022-06-30
- Inventor: Tracy S. MITCHELL , Michael L. Gosselin , Dasa Lipovsek , Rex Parker , Ray Camphausen , Jonathan H. Davis , David Fabrizio
- Applicant: Bristol-Myers Squibb Company
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Main IPC: C07K14/78
- IPC: C07K14/78 ; A61K47/64
Abstract:
The present invention relates to polypeptides which include tenth fibronectin type III domains (10Fn3) that binds to serum albumin, with south pole loop substitutions. The invention further relates to fusion molecules comprising a serum albumin-binding 10Fn3 joined to a heterologous protein for use in diagnostic and therapeutic applications.
Information query
