A system, method and apparatus to control memory devices over computer networks. For example, the system includes a first computer system and a second computer system. The second computer system manages cryptographic key; and the first computer system controls access to the second computer system. After establishing a secure authenticated connection between the first computer system and a client computer system, the client computer system may submit a request about a memory device. If the first computer system determines that that the client computer system is eligible to operate or control the memory device, the first computer system communicate with the second computer system to generate a response to the request using at least a cryptographic key stored in the second computer system in association with an unique identification of the memory device, without the cryptographic key being transmitted to outside of the second computer system.